PES Liquid Capsule Filter
Delivers superior throughput for broad challenging feed streams while minimize product loss in sterile filtration
- Dual layer and highly asymmetric PES membrane minimize pressure build-up while processing large volume fluids
- Structure design helps minimize dead zone which can cause loss of high value products
- Broad chemical compatibility, pH 1~14, allows use in a range of chemistries including acids and bases
- Product has been rigorously validated to product specification and industry standards with comprehensive documentation to support compliance
- Gamma capability ensures that integrators can connect these filters into any customer-specific, single-use assembly and provide it as a sterile, final assembled product
APPLICATIONS
PES Liquid Capsule Filter
Pharmaceutical
- Cell culture media and additives
- Bioburden or sterile filtration for various process fluids
- Process intermediates in mAb, vaccines, etc.
- Column or downstream unit protection
- High concentration buffers
- Bulk drug substances
- Protein solutions or formulations
Specifications
Drawings
Performance Data
Specifications
Style
- 50mm Disc
- Mini/1"/3"/5"/10" In-Line Capsules
Materials
- Media: Polyethersulfone
- Support: Polypropylene
- Core, cage, end caps: Polypropylene
- O-ring: N/A
- Sealing technology: Mechanical sealing with O-ring
- Polyethersulfone
- Polypropylene
- Polypropylene
- Silicone
- Thermal bonding without adhesives
Pore size
- 0.45+0.22 µm
- 0.65+0.22 µm
- 0.45+0.22 µm
- 0.65+0.22 µm
Normal effective filtration area
- 17.3 cm2
- Mini: 260 cm2
- 1": 560 cm2
- 3": 0.16 m2
- 5": 0.30 m2
- 10": 0.60m2
Integrity test
- Bubble point: N/A
- Water Diffusion @ 40 psi@ 25°C (77°F): N/A
- Mini: ≤ 1.8 mL/min
- 1" ≤ 3.8 mL/min
- 3" ≤ 6.8 mL/min
- 5" ≤ 11.5 mL/min
- 10" ≤ 21.5 mL/min
Maximum operating conditions
- Maximum operating pressure
- Maximum operating temperature
- 80 psi (5.5 bar) @ 25°C (77°F)
- 40 psi (2.8 bar) @ 60°C (140°F)
Multiple sterilization cycles
- 2 cycles of autoclave, 30 min at 130°C (266°F)
Gamma stability
- Gamma irradiation stable up to 45 kGy
Endotoxin releasing
- <0.25 EU/mL as determined by the LAL test, meeting the requirements of USP
Particulates*
- Particulate matter release meets the requirement of USP
Non-fiber releasing
- <0.5 mg/L post gamma and after a water flush, meeting the requirements of USP
TOC
- <0.5 mg/L post gamma and after a water flush, meeting the requirements of USP
Conductivity
- ≤1.3 μS/cm post gamma and after water flush, meeting the requirements of USP
Material toxicity
- All components meet the requirements of the USP , Biological Reactivity Test and the USP Reactivity Test for Class VI Plastics
Animal free
- Raw materials used to manufacture this product are not animal derived, meeting the EU directive for animal free CPMP EMA/410/01 and 21 CFR parts 189.5
Extractables
- Tested according to BioPhorum Operations Group (BPOG) guideline. Report is available upon request.
Quality
- Manufactured in accordance with ISO 9001 and ISO 13485 certified quality management system
Order Guide Information
| Please choose: | Industry | Retention rating (µm) | End Cap | Length (inch) | O-Ring | Skeleton |
|---|---|---|---|---|---|---|
| Food | 0.1 | 222/FIN | 5 | Silicon | PP | |
| Electron | 0.22 | 222/Flat | 10 | EPDM | Heat-Resistant Joints | |
| Pharmacy | 0.45 | 226/FIN | 20 | VITON | ||
| Chemicals | 0.65 | 226/Flat | 30 | |||
| 1.0 | DOE | 40 |
Date Sheet
Product Documentation
Published SEP 19, 2025
PES Liquid Capsule Filter
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Process fluid, filtration objectives, pore size rating, contaminant characteristics, operating temperature and pressure, flow rate, connection type, seal material, sterilization requirements, and existing cartridge specifications (if applicable).
